San Joaquin Delta College

The unique two-year program in Microscopy is offered to those students who, upon graduation, wish to find employment as technical support persons operating microscopes, doing sample preparation and interpretation, or in technical sales and marketing.

Link: San Joaquin Delta College

Madison Area Technical College

The Electron Microscopy program is a two-year program in which students learn to operate electron microscopes and related equipment, both scanning (SEM) and transmission (TEM). The program includes preparation of biological and material samples, communication skills, computer-image processing, X-ray microanalysis, and maintenance of electron microscopes and related equipment.

Link: Madison Area Technical College

The Nobel Prize in Physics 1986

The Royal Swedish Academy of Sciences has decided to award the 1986 Nobel Prize in Physics by one half to Professor. Ernst Ruska, Fritz-Haber-Institut der Max-Planck-Gesellschaft, Berlin, Federal Republic of Germany, for his fundamental work in electron optics, and for the design of the first electron microscope and the other half, jointly to Dr Gerd Binnig and Dr Heinrich Rohrer, IBM Research Laboratory, Zurich, Switzerland, for their design of the scanning tunnelling microscope.

Link: The Nobel Prize in Physics 1986

Intracellular Aspects of the Process of Protein Secretion

George E. Palade – Nobel Lecture, December 12, 1974

Link: Intracellular Aspects of the Process of Protein Secretion

Journey Into the Cell

History of electron microscopy at Rockefeller University and the

Link: Journey Into the Cell

James Hilier Bibliography and Archives

A complete listing of the publications of James Hillier who designed the first mass produced instrument and invented many techniques that extended the application of the electron microscope to a broad spectrum of sciences. Copies of many of the following are available from the Foundation for a nominal fee.

From: James Hillier Foundation
Link: James Hilier Bibliography and Archives

George E. Palade EM Slide Collection

The collection includes some of the earliest electron micrographs from Rockefeller University and Yale University. Many of the images are significant for their contribution to our understanding of cellular structure and processes. The images were used in the cell biology courses at Yale University by Drs. George Palade and Marilyn Farquhar. It was Dr. Palade's wish that the collection of images be freely available to students and scientists world-wide.

Link: George E. Palade EM Slide Collection

FEI Image Gallery

Scanning and transmission electron microscope images from FEI company.

From: FEI Company
Link: FEI Image Gallery

The Electron Microscope in Biology

Introduction to the Transmission Electron Microscope.

Link: The Electron Microscope in Biology

The Electron Microscope as an Illustration of the Wave Nature of the Electron

The transmission electron microscope uses principles that originated in light microscopy and which therefore rely on the properties of waves. These principles are illustrated.

Link: The Electron Microscope as an Illustration of the Wave Nature of the Electron

Electron Energy Loss Spectroscopy

Brief introduction to the Principle and application of Imaging electron energy loss spectroscopy

Link: Electron Energy Loss Spectroscopy

Dynamic Transmission Electron Microscope

Introduction to the Dynamic Transmission Electron Microscope (DTEM) at Lawrence Livermore Laboratories that provides the ability to image transient behaviors such as how a chemical reaction, structural deformation or phase transformation takes place with an unprecedented combination of spatial and temporal resolution: nanometers and nanoseconds.

Link: Dynamic Transmission Electron Microscope

Introduction to Electron Microscopy

Read the FEI booklet "An Introduction to Electron Microscopy", an excellent resource on electron microscopy and nanotechnology for students and teachers

From: FEI Company
Link: Introduction to Electron Microscopy

Disease Carriers: Explore the Microscopic World of Health Science

Learn about the science underlying public health issues by perusing -- and using -- digitized images on view.

Link: Disease Carriers: Explore the Microscopic World of Health Science

Virus Ultrastructure

This well done site includes principles of virus structure, Electron Microscopy:How images are created by negative staining, electron microscopy images, and lecture notes.

Link: Virus Ultrastructure

John Maxwell Cowley 1923–2004

Link: John Maxwell Cowley 1923–2004

James Hillier

James Hillier OC (August 22, 1915 – January 15, 2007) was a Canadian-born scientist and inventor who designed and built, with Albert Prebus, the first successful high-resolution electron microscope in North America in 1938.

Link: James Hillier

Keith R. Porter

Keith Roberts Porter (1912-1997) was a Canadian cell biologist. He did pioneering biology research using electron microscopy of cells [1], such as work on the 9 + 2 microtubule structure in the axoneme of cilia.

Link: Keith R. Porter

George E. Palade: Legacy of a Distinguished Scientist:

In the early 1950s, Palade’s utilization of the then new technologies, such as electron microscopy and ultracentrifugation,brought understanding of the cell to a new level.

Link: George E. Palade: Legacy of a Distinguished Scientist:

George E. Palade The Nobel Prize in Physiology or Medicine 1974 Autobiography

This autobiography/biography was written at the time of the award and later published in the book series Les Prix Nobel/Nobel Lectures.

Link: George E. Palade The Nobel Prize in Physiology or Medicine 1974 Autobiography

James Hillier: Electron Lens Correction Device

National Inventors Hall of Fame ™

Link: James Hillier: Electron Lens Correction Device

EM Outreach

Complete course notes.

Link: EM Outreach

About STEM

The history and overview section provides an introduction to STEM.

Link: About STEM

Development of 200kV Atomic Resolution Analytical Microscope

From: JEOL USA, Inc.
Link: Development of 200kV Atomic Resolution Analytical Microscope

Electron Microscopy For Chemists

Overview of the advances in transmission electron microscopes atomic level imaging and elemental analysis that move the TEM into the realm of analytical chemistry.

Link: Electron Microscopy For Chemists

Introduction to Fluctuation Microscopy

Fluctuation microscopy has been used to study disordered materials including amorphous Ge and silicon. This paper is a general introduction to the technique.

Link: Introduction to Fluctuation Microscopy

Tutorials in transmission electron microscopy

For biological and material scientists who are new to TEM, but need to learn to use the technique.

Link: Tutorials in transmission electron microscopy

Course Notes from Dr. Timothy S. Baker

Current course notes for electron microscopy in pdf and Powerpoint. The <em>Bottom Line</em> is especailly helpful and focuses basic concepts that are important for understanding the fundamental principles of transmission electron microscopy, biological specimen preparation, and three-dimensional image processing and reconstruction. Winter 2011 course is 3D Electron Microscopy of Macromolecules.

Link: Course Notes from Dr. Timothy S. Baker

Transmission Electron Microscopy (TEM)

This is a set of resources designed to accompany an introductory course on transmission electron microscopy. The level is appropriate for students with an understanding of some elementary physics.

Link: Transmission Electron Microscopy (TEM)

Learn to do TEM

Learn to use a transmission electron microscope...fast. This site has put together by John Rodenburg, who has been teaching graduate students to use TEMs for over twenty years (at the University of Cambridge, Sheffield Hallam and Sheffield Universities). Now includes a new section on TEM/STEM alignment.

Link: Learn to do TEM

Bioscience Microscopy Courses

Cource notes, protocols, and power point presentation for specimen preparation for scanning electron and transmission electon microscopy and overviews of instrumentation.

Link: Bioscience Microscopy Courses

All the Virology on the WWW

Link: All the Virology on the WWW